TB-500 Fragment (Ac-GDKPDAE) 17-23 10mg

Product Name: TB-500 Fragment 17-23

Sequence: Ac-Gly-Asp-Lys-Pro-Asp-Ala-Glu-NH2 (Ac-GDKPDAE)

Molecular Formula: C₃₈H₆₇N₉O₁₅

Molecular Weight: 889.0 g/mol

Purity: ≥ 99% (HPLC) Form: Lyophilized Powder

Quantity: 10 mg

Storage: Lyophilized at -20°C (long-term); reconstituted at 2-8°C (up to 2 weeks)

Appearance: White to off-white lyophilized powder

Solubility: Soluble in bacteriostatic water or sterile saline

Product Description

TB-500 Fragment 17-23 (Ac-GDKPDAE) is a shortened, N-terminally acetylated and C-terminally amidated synthetic derivative of the active core region (amino acids 17-23) of the naturally occurring thymosin beta-4 (TB-4) peptide.

This 7-amino-acid fragment contains the functional LKKTETQ-like motif believed to be primarily responsible for many of the actin-binding, cell-migration, and tissue-regenerative properties associated with full-length TB-500/TB-4 in preclinical research models.

Because of its dramatically reduced size compared to the 43-amino-acid parent molecule, the TB-500 Fragment 17-23 exhibits:

• Improved stability against enzymatic degradation
• Potentially enhanced tissue penetration
• Greater resistance to rapid clearance
• Simplified handling and reconstitution
• Potentially offering superior bioavailability and a longer half-life

Common Research Applications

(For laboratory and in vitro research use only – not for human or veterinary therapeutic use)

• Actin sequestration and cytoskeleton remodeling studies
• Cell migration and wound-healing model research
• Angiogenesis and neovascularization investigations
• Anti-inflammatory pathway exploration
• Fibrosis and tissue regeneration preclinical models
• Dermatological and corneal injury research models