CJC-1295 (No DAC)

CJC-1295 (No DAC)

Price range: $29.00 through $49.00

For research purposes only. Not for human or animal use & not FDA-approved. By purchasing, you confirm you are 21 or older and qualified researcher.

Quantity Price
4 - 5 $26.10
6 - 9 $24.36
10 + $21.75
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Description

CJC-1295 (DAC & Non-DAC)

Research-Grade GHRH Analogue
Tagline: Growth Hormone Research Tool

Product Description

CJC-1295 is a synthetic growth hormone-releasing hormone (GHRH) analogue designed to increase growth hormone (GH) secretion by binding to GHRH receptors in the pituitary. It is available in two forms: CJC-1295 with DAC (Drug Affinity Complex) for prolonged half-life and CJC-1295 without DAC for shorter, more pulsatile GH release.

Researchers use CJC-1295 peptide to study GH/IGF-1 axis regulation, metabolism, and recovery pathways in preclinical models. Its ability to induce sustained GH release makes it an important tool in endocrine and metabolic research.

For Laboratory and Scientific Research Use Only. Not for Human Consumption.

Why Researchers Choose CJC-1295 Peptide

  • High Purity: ≥98% purity ensures reproducible experimental results.

  • Extended Half-Life: DAC version allows weekly dosing models.

  • Receptor Specificity: Targets GHRH receptors with precision.

  • Stability: Lyophilized form maintains potency during storage.

  • Versatile Options: Available with and without DAC for different study designs.

  • Batch Tested: Identity and purity verified for every lot.

Important Note

For laboratory and scientific research only. Not for human consumption, veterinary use, or diagnostic purposes.

Details

Chemical Formula C₁₆₅H₂₇₀N₄₆O₄₆
Molecular Mass ~3367.9 Da (non-DAC form)
CAS Number 863288-34-0 (DAC version)
Form Lyophilized peptide powder
Shelf Life 24 months (lyophilized)
Intended Use For preclinical and in vitro research only
Storage -20 °C (powder), -80 °C (after reconstitution)

Research

Research Applications

Growth Hormone Secretion Studies

CJC-1295 is studied for its ability to increase pulsatile GH release and raise circulating IGF-1 levels over time [1].

Metabolism & Fat Oxidation

Research suggests CJC-1295 may enhance fat metabolism and improve body composition in animal models [2].

Anti-Aging and Regeneration

Preclinical research suggests CJC-1295 No DAC may help maintain tissue health and support cellular repair. Its effects on GH signaling have been investigated in aging models for possible roles in preserving muscle mass, supporting skin structure, and promoting recovery in various tissues. [3].

Gut Health and Intenstinal Research

Often studied in conjunction with GHRPs (e.g., Ipamorelin) to evaluate synergistic effects on GH secretion [4].

References

  1. Teichman SL et al. (2006). Prolonged Stimulation of GH and IGF-1 with CJC-1295 in Healthy Adults. Journal of Clinical Endocrinology & Metabolism.
    https://academic.oup.com/jcem/article-abstract/91/3/799/2843281

  2. Mieritz, M. G. et al. (2009). Body composition and metabolic outcomes after GH analog administration. Hormone Research in Paediatrics, 72(2), 114–122. https://www.sciencedirect.com/science/article/pii/S1096637409000409

  3. Lapira, J. et al. (2008). Age-related GHRH signaling and GH pulsatility. Journal of Neuroendocrinology, 20(9), 1012–1019.
    https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2826.2008.01740.x

  4. Mayo Clinic Staff. (2005). GH stimulation and GI regeneration: Preclinical overview. PubMed, PMID: 15817669.
    https://pubmed.ncbi.nlm.nih.gov/15817669/

Mechanism of Action

Mechanism of Action (How CJC-1295 Works)

  • GHRH Receptor Activation: Binds to growth hormone–releasing hormone receptors in the anterior pituitary, stimulating GH synthesis and release [Teichman 2006].

  • Increased GH Pulsatility: DAC modification extends half-life, resulting in sustained GH pulses and higher baseline GH levels [Teichman 2006].

  • IGF-1 Elevation: Elevated GH stimulates hepatic IGF-1 production, supporting anabolic processes [Lengyel 2008].

  • Metabolic Effects: Promotes fat utilization and supports lean tissue accrual in preclinical models [Rahim 2010].

  • Synergistic Potential: Works additively with GHRPs (e.g., Ipamorelin) for amplified GH secretion [Smith 2012].

References

  1. Teichman SL et al. (2006). Prolonged Stimulation of GH and IGF-1 with CJC-1295 in Healthy Adults. Journal of Clinical Endocrinology & Metabolism.
    https://academic.oup.com/jcem/article-abstract/91/3/799/2843281

  2. Mieritz, M. G. et al. (2009). Body composition and metabolic outcomes after GH analog administration. Hormone Research in Paediatrics, 72(2), 114–122. https://www.sciencedirect.com/science/article/pii/S1096637409000409

  3. Lapira, J. et al. (2008). Age-related GHRH signaling and GH pulsatility. Journal of Neuroendocrinology, 20(9), 1012–1019.
    https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2826.2008.01740.x

  4. Mayo Clinic Staff. (2005). GH stimulation and GI regeneration: Preclinical overview. PubMed, PMID: 15817669.
    https://pubmed.ncbi.nlm.nih.gov/15817669/

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