Semax/Selank

Semax/Selank

Price range: $59.00 through $89.00

For research purposes only. Not for human or animal use & not FDA-approved. By purchasing, you confirm you are 21 or older and qualified researcher.

Quantity Price
4 - 5 $53.10
6 - 9 $49.56
10 + $44.25
Money Back Guarantee Guaranteed Quality Customer Support Fast Shipping
SKU: N/A Categories: , , , , ,

Description

Semax/Selank (10 mg)

Research-Grade Dual Neuropeptide Complex
Tagline: Cognitive, Anxiolytic & Neuroprotective Research

Product Description

Semax/Selank is a balanced combination of two synthetic heptapeptides — Semax, derived from ACTH(4-10), and Selank, derived from tuftsin. This dual formulation provides a unique research tool for studying cognitive enhancement, anxiolytic regulation, and neurotrophic activity in preclinical models.

By combining Semax’s neurotrophic and cognitive-enhancing effects with Selank’s GABAergic and immunomodulatory mechanisms, this compound is used in studies on stress resilience, learning and memory, neurotransmitter modulation, and neuroinflammation.

For Laboratory and Scientific Research Use Only. Not for Human Consumption.

Why Researchers Choose Semax/Selank

  • Dual Mechanism Model: Combines neurotrophic and anxiolytic peptide actions.

  • Synergistic Effect: Supports both BDNF upregulation and GABAergic modulation.

  • Cognitive Research Tool: Used to study learning, attention, and memory retention.

  • Neuroprotective Applications: Investigated for ischemia, oxidative stress, and neuroinflammation.

  • High Purity: ≥98% purity confirmed via HPLC and mass spectrometry.

Important Note

For laboratory and scientific research only. Not for human consumption, diagnostic, or therapeutic use.

Details

Compound Name Semax/Selank (Dual Peptide Complex)
Chemical Composition 1:1 ratio of Semax (Met-Glu-His-Phe-Pro-Gly-Pro) and Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro)
Chemical Formula Approx. C70H110N20O20S
Molecular Mass ~1,640 Da (combined)
Form Lyophilized peptide powder
Storage Conditions –20 °C (dry); 2–8 °C (after reconstitution)
Intended Research Use Neurotrophic, anxiolytic, and cognitive studies

Research

Research Applications

Cognitive Function & Neuroplasticity

Semax enhances BDNF (brain-derived neurotrophic factor) and NGF (nerve growth factor) expression, supporting synaptic plasticity and memory formation. Combined with Selank, it provides synergistic effects on learning, focus, and cognitive resilience under stress [Inozemtseva 2008].

Anxiolytic & GABAergic Modulation

Selank acts on GABAergic neurotransmission and reduces stress-related overactivation of the hypothalamic–pituitary–adrenal (HPA) axis, producing anxiolytic effects without sedation [Filatova 2017].

Neuroprotection & Stress Adaptation

Both peptides contribute to neuroprotection by reducing oxidative stress, neuroinflammation, and ischemic injury. Studies show enhanced antioxidant enzyme activity and normalization of serotonin and dopamine turnover [Myasoedov 2009].

Immunomodulation & Anti-Inflammatory Effects

Selank’s tuftsin-derived structure influences cytokine expression, while Semax regulates immune–neuro interface pathways, providing dual modulation of IL-6, TNF-α, and IL-10 [Volkova 2016].

References

  1. Inozemtseva LS, et al. (2008). Semax Regulates BDNF Expression in the Rat Hippocampus Following Hypoxic Stress. Doklady Biological Sciences.
    https://pubmed.ncbi.nlm.nih.gov/18806861

  2. Filatova E, et al. (2017). GABA, Selank, and Olanzapine Affect Genes Involved in GABAergic Transmission in IMR-32 Cells. Frontiers in Pharmacology.
    https://www.frontiersin.org/articles/10.3389/fphar.2017.00089/full

  3. Myasoedov NF, et al. (2009). Peptide Neuroprotectors as Regulators of the Brain Stress System: Role of Semax. Biochemistry (Moscow).
    https://pubmed.ncbi.nlm.nih.gov/19548543

  4. Volkova A, et al. (2016). Selank Administration Affects Expression of Genes Involved in GABAergic Neurotransmission. Frontiers in Pharmacology.
    https://www.frontiersin.org/articles/10.3389/fphar.2016.00031/full

  5. Ashmarin IP, et al. (2005). Peptidergic Regulation of Brain Functions: Lessons from ACTH Analogues. Neuroscience and Behavioral Physiology.
    https://link.springer.com/article/10.1007/s11055-005-0078-3

Mechanism of Action

Mechanism of Action

  • BDNF & NGF Upregulation: Semax increases neurotrophin gene expression, enhancing neuron growth and repair [Inozemtseva 2008].

  • GABAergic Activity: Selank modulates GABA-A receptor expression, promoting inhibitory tone and reducing anxiety [Filatova 2017].

  • Neurotransmitter Regulation: Both peptides normalize dopamine, serotonin, and norepinephrine levels in cortical and limbic regions [Ashmarin 2005].

  • Anti-Inflammatory Modulation: Suppresses pro-inflammatory cytokines and supports immune homeostasis [Volkova 2016].

  • Neuroprotective Signaling: Enhances antioxidant enzyme expression and reduces ischemic neuronal damage [Myasoedov 2009].

References

  1. Inozemtseva LS, et al. (2008). Semax Regulates BDNF Expression in the Rat Hippocampus Following Hypoxic Stress. Doklady Biological Sciences.
    https://pubmed.ncbi.nlm.nih.gov/18806861

  2. Filatova E, et al. (2017). GABA, Selank, and Olanzapine Affect Genes Involved in GABAergic Transmission in IMR-32 Cells. Frontiers in Pharmacology.
    https://www.frontiersin.org/articles/10.3389/fphar.2017.00089/full

  3. Myasoedov NF, et al. (2009). Peptide Neuroprotectors as Regulators of the Brain Stress System: Role of Semax. Biochemistry (Moscow).
    https://pubmed.ncbi.nlm.nih.gov/19548543

  4. Volkova A, et al. (2016). Selank Administration Affects Expression of Genes Involved in GABAergic Neurotransmission. Frontiers in Pharmacology.
    https://www.frontiersin.org/articles/10.3389/fphar.2016.00031/full

  5. Ashmarin IP, et al. (2005). Peptidergic Regulation of Brain Functions: Lessons from ACTH Analogues. Neuroscience and Behavioral Physiology.
    https://link.springer.com/article/10.1007/s11055-005-0078-3

Certificate of Authenticity

Endotoxin Result

Related products

  • MOTS-c
  • Selank
  • GLOW - 70mg
  • §-31