GHRP-6 - 5mg

GHRP-6 – 5mg

$29.00

For research purposes only. Not for human or animal use & not FDA-approved. By purchasing, you confirm you are 21 or older and qualified researcher.

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Description

GHRP-6 (Growth Hormone Releasing Peptide-6)

Research-Grade Hexapeptide
Tagline: GH Secretion & Appetite Research

Product Description

GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic hexapeptide and potent ghrelin receptor (GHS-R1a) agonist, widely used in research to study growth hormone (GH) secretion, appetite regulation, and metabolic signaling.

Researchers utilize GHRP-6 in preclinical and in vitro models to explore GH axis physiology, IGF-1 production, ghrelin-mediated hunger response, and tissue regeneration pathways. Its activity makes it a valuable tool in endocrinology, metabolism, and muscle growth studies.

For Laboratory and Scientific Research Use Only. Not for Human Consumption.

Why Researchers Choose GHRP-6

  • Potent GH Secretagogue: Stimulates pulsatile GH release via pituitary and hypothalamic pathways.

  • Ghrelin Receptor Agonist: Activates GHS-R1a, enabling appetite and metabolic research.

  • Synergistic Potential: Often studied with GHRH analogues like Sermorelin or CJC-1295 for amplified GH release.

  • Muscle & Tissue Research: Used to model GH/IGF-1–driven recovery and regeneration.

  • Batch Verified: ≥98% purity, tested by HPLC and mass spectrometry.

Important Note

For laboratory and scientific research only. Not for human consumption, veterinary use, or diagnostic purposes.

Details

Chemical Formula C₄₆H₅₆N₁₂O₆
Molecular Mass 873.0 Da
CAS Number 87616-84-0
Form Lyophilized peptide powder
Shelf Life 24 months (lyophilized)
Intended Use For preclinical and in vitro research only
Storage -20 °C (dry powder), -80 °C (after reconstitution)

Research

Research Applications

Growth Hormone Axis Studies

GHRP-6 stimulates GH release independently of GHRH, providing a model to study pituitary responsiveness and GH pulsatility [1].

IGF-1 Production & Anabolism

Used in studies to measure downstream effects on hepatic IGF-1 production and protein synthesis [2].

Appetite & Ghrelin Research

Activates ghrelin receptors, increasing hunger and food intake in animal models — useful in cachexia and metabolism research [3].

Muscle & Tissue Regeneration

Explored for its ability to accelerate muscle repair and connective tissue recovery through GH/IGF-1 pathways [4].

References

  1. Smith RG et al. (1997). GHRP-6 as a Potent GH Secretagogue. Endocrinology.
    https://link.springer.com/chapter/10.1007/978-1-59259-015-5_2

  2. Bowers CY et al. (1990). GHRP-6 and IGF-1 Production in Humans. J Clin Endocrinol Metab.
    https://karger.com/hrp/article/51/Suppl.%203/1/371582/Growth-Hormone-Releasing-Substances-Types-and

  3. Kojima M et al. (1999). Discovery of Ghrelin and its Receptor. Nature.
    https://reference.medscape.com/medline/abstract/10604470

  4. Nass R et al. (2008). GH Secretagogues and Tissue Repair Models. Hormone Research.
    https://link.springer.com/chapter/10.1007/978-1-59259-015-5_3

Mechanism of Action

Mechanism of Action (How GHRP-6 Works)

  • Ghrelin Receptor Agonism: Binds GHS-R1a on pituitary somatotrophs and hypothalamic neurons, triggering GH release [Smith 1997].

  • Synergistic with GHRH: Acts via a distinct receptor pathway, amplifying GH pulse amplitude when combined with GHRH analogues [Bowers 1990].

  • Hypothalamic Stimulation: Reduces somatostatin tone, increasing net GH secretion [Smith 1997].

  • Hunger Signaling: Activates hypothalamic NPY/AgRP neurons, stimulating appetite [Kojima 1999].

  • Anabolic Pathways: Leads to elevated IGF-1 and enhanced protein synthesis, supporting muscle and tissue repair [Nass 2008].

References

  1. Smith RG et al. (1997). GHRP-6 as a Potent GH Secretagogue. Endocrinology.
    https://link.springer.com/chapter/10.1007/978-1-59259-015-5_2

  2. Bowers CY et al. (1990). GHRP-6 and IGF-1 Production in Humans. J Clin Endocrinol Metab.
    https://karger.com/hrp/article/51/Suppl.%203/1/371582/Growth-Hormone-Releasing-Substances-Types-and

  3. Kojima M et al. (1999). Discovery of Ghrelin and its Receptor. Nature.
    https://reference.medscape.com/medline/abstract/10604470

  4. Nass R et al. (2008). GH Secretagogues and Tissue Repair Models. Hormone Research.
    https://link.springer.com/chapter/10.1007/978-1-59259-015-5_3

Certificate of Authenticity

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